HMGB1 Studies in wound healing. SOURCE: Bio-Quant, Inc. HMGB1 Studies in wound healing.

Bio3 Research S.r.l. (Milano – Italy), is pleased to announce the positive preclinical studies outcome (conducted by the CRO Bio-Quant Inc. La Jolla/CA) obtained with HMGB1 in wound healing in mice and pigs (Vehicle and PDGF as control) which confirms the protein high potential in tissue remodeling. HMGB1 project has demonstrated in-vitro and in-vivo the dual ability of the protein to accelerate the wound healing process and to control the remodeling of collagen and fibroblasts. Bio3 Research has also tested in animals (rabbits) HMGB1 for its use in cartilage repair with encouraging results.